Yemen's Iran-backed Huthi rebels have been firing missiles and drones at Israel and ships in the Red Sea and Gulf of Aden in what they describe as solidarity with Palestinians since the war in the Gaza Strip broke out in October of last year.
In recent weeks, they have claimed to have fired several missiles at Israel, triggering retaliatory strikes from Israel targeting the rebels' strategic assets and infrastructure.
"Following the sirens that sounded a short while ago in central Israel, a missile launched from Yemen was intercepted by the IAF (air force) prior to crossing into Israeli territory," the Israeli military said in a statement.
Israel's emergency service provider, Magen David Adom, reported that it had received no reports of any casualties so far.
On Saturday, Israel intercepted a similar missile launched from Yemen.
The Iran-backed Huthis have controlled large parts of Yemen since seizing Sanaa and ousting the government in 2014.
They have stepped up their attacks since November's ceasefire between Israel and another Iran-backed group, Hezbollah in Lebanon.
Israel has also struck Yemen, including targeting Sanaa's international airport on Thursday.
An Israeli statement said its targets included "military infrastructure" at the airport and power stations in Sanaa and Hodeida -- a major entry point for humanitarian aid -- as well as other facilities at several ports.
Huthis use these sites "to smuggle Iranian weapons into the region and for the entry of senior Iranian officials", the statement said.
Israeli Prime Minister Benjamin Netanyahu has warned the Huthis, saying that Israeli strikes against them would "continue until the job is done".
"We are determined to cut this branch of terrorism from the Iranian axis of evil," he said in a video statement last week.
Defence Minister Israel Katz also recently declared: "We will hunt down all of the Huthis' leaders -- nobody will be able to evade the long arm of Israel."
The latest warnings from top Israeli officials came after a missile fired by the Huthis wounded 16 people in Israel's main commercial city of Tel Aviv.
That attack prompted strikes by the United States against the rebels in Sanaa.
American and British forces have repeatedly struck rebel targets in Yemen this year in response to Huthi attacks on shipping in Red Sea-area waters vital to global trade.
In July, a Huthi drone attack on Tel Aviv killed an Israeli civilian, prompting the first Israeli retaliation on Hodeida.
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